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The IP3 being water solublediffuses to the cytosol and mobilizes Ca2+ fromendoplasmic reticular depots (Fig. pathway A illustrates reabsorption of filtered chemicals byuptake into the pT cell across the brush-border plasma membrane(BBM) and then efflux from the cell into the renal plasma and inter-stitial space by transport across the basolateral plasma membrane(BLM)
pathway A illustrates reabsorption of filtered chemicals byuptake into the pT cell across the brush-border plasma membrane(BBM) and then efflux from the cell into the renal plasma and inter-stitial space by transport across the basolateral plasma membrane(BLM).
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The ‘firstgeneration’ fluoroquinolones (FQs) introducedin 1980s have one fluoro substitution. Common in primary biliary cirrhosis and obstructive jaundice
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